Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jul 2011
Multicenter StudyN-terminal-pro-BNP in critically ill patients with acute respiratory failure: a prospective cohort study.
The aim of this study was to evaluate the prognostic value of plasma N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) in unselected critically ill patients with acute respiratory failure (ARF). ⋯ NT-pro-BNP on admission is commonly elevated and independently associated with 90-day mortality in critically ill ARF patients. However, the routine use of NT-pro-BNP for prognostic purpose does not seem to add value to clinical data in ARF patients.
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Acta Anaesthesiol Scand · Jul 2011
Randomized Controlled Trial Multicenter StudyTrain-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadex.
Sugammadex reverses rocuronium-induced neuromuscular block (NMB). In all published studies investigating sugammadex, the primary outcome parameter was a train-of-four (TOF) ratio of 0.9. The recovery time of T1 was not described. This retrospective investigation describes the recovery of T1 vs. TOF ratio after the reversal of NMB with sugammadex. ⋯ After the reversal of NMB by sugammadex, full recovery of the TOF ratio is possible when T1 is still depressed. The TOF ratio as the only measurement for the adequate reversal of NMB by sugammadex may not always be reliable. Further investigations for clinical implications are needed.
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Acta Anaesthesiol Scand · May 2011
Multicenter StudySerum zinc in critically ill adult patients with acute respiratory failure.
Zinc deficiency leads to susceptibility to infections and may affect pulmonary epithelial cell integrity. Low zinc levels have also been associated with a degree of organ failure and decreased survival in critically ill children. Accordingly, the purpose of the study was to assess serum zinc in adult patients with acute respiratory failure, its association with ventilatory support time, intensive care unit (ICU) length of stay (LOS), organ dysfunction and 30-day mortality. ⋯ Serum zinc on initiation of ventilation had no predictive value for 30-day mortality, ventilatory support time or intensive care unit LOS.
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Acta Anaesthesiol Scand · Feb 2011
Multicenter StudyPatient satisfaction with care in the intensive care unit: can we rely on proxies?
To investigate whether next of kin can be addressed as proxy to assess patients' satisfaction with care in the intensive care unit (ICU). ⋯ If the patient is unable to rate his satisfaction with care in the ICU, next of kin may be taken as an appropriate surrogate.
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Acta Anaesthesiol Scand · Aug 2010
Multicenter StudyLactate concentrations in the rectal lumen in patients in early septic shock.
Previously, we observed that rectal luminal lactate was higher in non-survivors compared with survivors of severe sepsis or septic shock persisting >24 h. The present study was initiated to further investigate this tentative association between rectal luminal lactate and mortality in a larger population of patients in early septic shock. ⋯ In this prospective, observational study of unselected patients with early septic shock, there was no difference in the concentration of lactate in the rectal lumen between non-survivors and survivors.