Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialPatient-controlled analgesia with oxycodone in the treatment of postcraniotomy pain.
Moderate to severe pain occurs after craniotomy in 60% of patients. We evaluated the feasibility and safety of patient-controlled analgesia (PCA) with oxycodone in neurosurgical patients, and compared the efficacy of paracetamol with ketoprofen. ⋯ PCA with oxycodone is a suitable method for pain control after craniotomy. No progressive hypoventilation, desaturation or excessive sedation were encountered. Ketoprofen appeared to be more effective than paracetamol.
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Acta Anaesthesiol Scand · Jan 1999
Comparative StudyIntact proprioception and control of labour pain during epidural analgesia.
Accurate proprioception is critical while walking, yet an ambulatory epidural regimen that provides adequate analgesia for labour while simultaneously preserving proprioceptive input has not been described. ⋯ This study confirms that the addition of lumbar epidural fentanyl 100 micrograms to 15 mg of epidural bupivacaine provides good control of labour pain with no motor block and establishes that this combination preserves dorsal column sensory function.
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Acta Anaesthesiol Scand · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialA large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol.
Rocuronium has an onset of action more rapid than other non-depolarizing neuromuscular blocking agents, but it is unclear whether it and succinylcholine give equivalent intubating conditions during rapid-sequence induction of anaesthesia. We performed this study to answer the question--are there clinically relevant differences between the use of rocuronium and succinylcholine to secure acceptable intubating conditions during rapid-sequence induction of anaesthesia with propofol? ⋯ Rocuronium 1.0 mg/kg given along with propofol in a rapid-sequence induction of anaesthesia is clinically equivalent to succinylcholine 1.0 mg/kg.
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Acta Anaesthesiol Scand · Jan 1999
Randomized Controlled Trial Clinical TrialIntra-articular buprenorphine after knee arthroscopy. A randomised, prospective, double-blind study.
Demonstration of peripheral opioid receptors in inflamed synovia supports the concept of peripheral opioid analgesia. The aim of this study was to evaluate the analgesic effect of intra-articular administration of buprenorphine after knee arthroscopy. ⋯ Intra-articular buprenorphine and i.a. bupivacaine, both produced equally good postoperative pain control and allowed a significant reduction of analgesic requirement after knee arthroscopy.
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Acta Anaesthesiol Scand · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialPeroperative treatment with i.v. ketoprofen reduces pain and vomiting in children after strabismus surgery.
Strabismus surgery is associated with both pain and vomiting. Ketoprofen is widely used in adults to treat acute pain, but there are only few reports of its use in children. This randomised, double-blind, placebo-controlled, parallel group study was designed to investigate the analgesic effect of i.v. ketoprofen and its effect on the incidence of vomiting in children after day-case strabismus surgery. ⋯ We concluded that ketoprofen administered i.v. during the operation produced analgesia and reduced opioid consumption and the incidence of vomiting in children after strabismus surgery.