Journal of paediatrics and child health
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J Paediatr Child Health · Nov 2014
Review Meta AnalysisDo antidepressants make children and adolescents suicidal?
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J Paediatr Child Health · Feb 2014
Review Meta AnalysisRestrictive versus liberal red blood cell transfusion thresholds in very low birth weight infants: a systematic review and meta-analysis.
A systematic review was conducted to examine the effects of restrictive versus liberal red blood cell (RBC) transfusion thresholds on clinically important outcomes in very low birth weight (VLBW) infants. ⋯ Restrictive RBC transfusion thresholds in VLBW infants may be utilised without incurring clinically important increases in the risk of death or major short-term neonatal morbidities.
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J Paediatr Child Health · Jan 2008
Review Meta AnalysisAcute treatment of paediatric migraine: a meta-analysis of efficacy.
To undertake a meta-analysis of all randomised controlled trials (RCTs) on the acute pharmacologic treatment of children and adolescents with migraine headache. ⋯ Despite the pharmacological options for the management of acute migraine, few RCTs in the paediatric population exist. Composite data demonstrate that only ibuprofen and sumatriptan are significantly more effective than placebo in the generation of headache relief in children and adolescents.
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J Paediatr Child Health · Aug 1999
Meta AnalysisPost-extubation prophylactic nasal continuous positive airway pressure in preterm infants: systematic review and meta-analysis.
To determine whether management with nasal continuous positive airway pressure (NCPAP) in preterm infants having their endotracheal tube removed following a period of intermittent positive pressure ventilation (IPPV), leads to an increased proportion remaining free of additional ventilatory support, compared to extubation directly to headbox oxygen. ⋯ Nasal CPAP is effective in preventing failure of extubation in preterm infants following a period of endotracheal intubation and IPPV. Further definition of the patient gestational age and weight groups to whom these results apply is required. Optimal levels of NCPAP as well as methods of administration remain to be determined.