Annals of oncology : official journal of the European Society for Medical Oncology
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Randomized Controlled Trial Comparative Study Clinical Trial
A phase III randomised study comparing two different dose-intensity regimens as induction chemotherapy followed by thoracic irradiation in patients with advanced locoregional non-small-cell lung cancer.
The aim of this study was to determine the role of chemotherapy dose intensity in patients with initially unresectable non-metastatic non-small-cell lung cancer (NSCLC), with survival as primary end point, by testing two different regimens as induction chemotherapy followed by thoracic irradiation. ⋯ High dose-intensity induction chemotherapy does not improve survival in initially unresectable non metastatic NSCLC.