Acta dermato-venereologica
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Acta Derm. Venereol. · Jan 1990
Randomized Controlled Trial Clinical TrialPain control in the surgical debridement of leg ulcers by the use of a topical lidocaine--prilocaine cream, EMLA.
The analgesic effect of EMLA 5% cream for surgical cleansing of leg ulcers was investigated in an open study and in a double-blind comparison with placebo. Eighty patients with ulcers of venous or arterial origin participated. The cream was applied under occlusion and removed before cleansing. ⋯ The median VAS pain scores for EMLA and placebo were 18.5 and 84 mm (p less than 0.01). There were no severe adverse reactions. The results show that there is a need for pain control in surgical debridement of leg ulcers and that EMLA cream gives satisfactory analgesia for this procedure.