Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Jan 1999
Comparative StudyRapid and simultaneous activation of Stat3 and production of interleukin 6 in resuscitated hemorrhagic shock.
The inflammatory response of the liver to hemorrhagic shock includes the production of acute phase proteins and a variety of mediators, such as the cytokine interleukin (IL)-6. The transcription of acute phase protein genes in hepatocytes has been shown to be activated by Stat3, one of six distinct signal transducers and activators of transcription (STAT) proteins. ⋯ In this study, we examined whether or not Stat3 was activated and IL-6 mRNA produced in the liver of rats subjected to hemorrhagic shock and whether or not both phases of shock, the ischemic and the resuscitation phases, were required. We report here that Stat3 activation and increased IL-6 expression required resuscitation and displayed identical kinetics following resuscitation, suggesting that liver production of IL-6 was responsible for liver Stat3 activation in hemorrhagic shock.
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Three of 12 nonrheumatoid patients with bicipital radial bursitis had recurrent and recalcitrant symptoms and underwent operative treatment. Preoperative computed tomogram showed an anterior distended synovial cyst at the level of the radial tubercle. ⋯ Excision of the distended bursa and closing the capsular defect lead to excellent results. An antecubital cyst resulting from an acute or chronic tear of the anterior capsule at the sacciform recess may communicate with the bicipital radial bursa and become the cause of recurrent and recalcitrant symptoms.
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Arch Orthop Trauma Surg · Jan 1999
Case ReportsIsolated posterolateral dislocation of the radial head in a boy.
Isolated dislocation of the radial head in children is a rare injury. We report an isolated posterolateral dislocation of the radial head in a boy after a fall on the outstretched arm. Immediate closed reduction and early active motion achieved satisfactory results.
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Arch Orthop Trauma Surg · Jan 1999
Case ReportsNon-union of undisplaced radial neck fracture in a rheumatoid patient.
Non-union of an undisplaced fracture of the radial neck in a rheumatoid patient is presented. Possible causes are discussed, and the literature reviewed.
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Arch Orthop Trauma Surg · Jan 1999
Clinical TrialFour-part posterior fracture--dislocations of the shoulder. Treatment by limited open reduction and percutaneous stabilization.
Ten patients who had been treated by limited open reduction and percutaneous stabilization for four-part posterior fracture-dislocation of the shoulder were followed-up for an average of 3.2 years postoperatively. According to the criteria of Neer, the result was excellent in nine patients, with an average Constant score of 95.7. There was one failure who showed complete avascular necrosis. All patients with excellent results had at least 1 mm of the neck portion of the head fragment intact.