Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Sep 2007
Rofecoxib inhibits heterotopic ossification after total hip arthroplasty.
Nonsteroidal anti-inflammatory drugs (NSAIDs) prevent heterotopic ossification but gastrointestinal complaints are frequently. Selective cyclooxygenase-2 (COX-2) inhibiting NSAID produce less gastrointestinal side effects. ⋯ Using a two-stage study design for phase 2 clinical trials, a 7-day treatment of a COX-2 inhibitor (rofecoxib) prevents effectively the formation of heterotopic ossification after cemented primary total hip arthroplasty.
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Arch Orthop Trauma Surg · Sep 2007
Case ReportsDiffuse idiopathic skeletal hyperostosis as a cause of acute respiratory distress in early postoperative period of total knee arthroplasty.
Diffuse idiopathic skeletal hyperostosis (DISH) is a common disorder among the elderly. The diagnosis is made on radiological findings and most of the cases are asymptomatic. ⋯ The acute occurrence of symptoms after general anesthesia is a rare manifestation of the disease. Radiological findings and the result of surgical resection of anterior cervical osteophytes are discussed.
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Arch Orthop Trauma Surg · Sep 2007
Case ReportsSliding hip screw in pelvis: a rare intra-operative complication.
We are presenting an unusual intra-operative complication of penetration of sliding hip screw (SHS) into the pelvis during fixation of an intertrochanteric fracture neck of femur in a 78-year-old man along with the technique of retrieving it.
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Arch Orthop Trauma Surg · Sep 2007
The effect of zymosan and the protective effect of various antioxidants on fracture healing in rats.
To investigate the effects of free oxygen radicals and various antioxidants on bone healing after experimental formation of fracture. ⋯ Free oxygen radicals demonstrate a negative effect on fracture healing and vitamin C (an antioxidant) partially prevents the negative effect of zymosan on fracture healing.
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Arch Orthop Trauma Surg · Aug 2007
Case ReportsCompartment syndrome in the hand due to extravasation of contrast material.
Extravasation of contrast material is a well-recognized complication of contrast-enhanced imaging studies. Most extravasations result only in minimal swelling or erythema; however, severe skin necrosis, ulceration and compartment syndrome may occur with extravasation of large volumes. This article presents a patient in whom extravasation developed after computed tomography (CT) contrast material was injected intravenously in the dorsum of the hand. ⋯ In follow-up, the patient regained full use of the hand. Although the use of contrast material has significantly improved the diagnostic accuracy of CT, anaphylaxis and contrast material extravasation are important complications. Selection of non-ionic contrast material, careful evaluation of the intravenous administration site and close monitoring of the patient during contrast material injection may help minimize or prevent extravasation injuries.