Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Jan 1979
Randomized Controlled Trial Clinical TrialBromocriptine treatment of the premenstrual syndrome.
Bromocriptine, 2.5 mg twice a day was tested for its effect on premenstrual tension in a random double-blind cross-over trial. 1. The compound tended to lessen the symptoms, especially mastodynia. 2. Serum prolactin levels around the upper limit of the normal range were significantly lowered. ⋯ Serum estradiol-17-beta and progesterone did not change during treatment. 4. The bromocriptine-treated cycles were all ovulatory according to basal temperature levels. The luteal phase was prolonged when serum FSH was raised.
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Acta Obstet Gynecol Scand · Jan 1977
Randomized Controlled Trial Clinical TrialInhibition of puerperal lactation. A double blind study of bromocriptine and placebo.
Bromocriptine and placebo were randomly allocated for three weeks to 52 postpartum patients requiring lactation suppression. Bromocriptine significantly lowered plasma prolactin levels and suppressed breast milk, breast pain and engorgement quicker than placebo. No side-effects were noted and rebound lactation did not occur. Menstruation appeared to re-start sooner when Bromocriptine was given.