Cancer causes & control : CCC
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Cancer Causes Control · May 2004
ReviewDietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence.
This study reviews epidemiological and experimental works dealing with the effects of dietary n -6 or n -3 polyunsaturated fatty acids (PUFA) on prostate cancer (PCa) development and PCa risk. ⋯ Long-chain n -3 PUFA from fish are possible promising nutrients for the dietary prevention of PCa, but to-date with little epidemiological support. In contrast, studies suggest that alpha -linolenic acid intake might be a risk factor. New work, both epidemiological and experimental, is awaited to clarify these results.
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In Korea, male smoking prevalence is among the world's highest, and mortality rates from smoking-caused cancers, particularly lung cancer, are escalating. This cohort study examined the effects of cigarette smoking on the risk of cancer mortality and incidence, and characterized the relationship of cancer risk with the amount and duration of cigarette smoking. ⋯ In Korea, smoking is an independent risk factor for a number of major cancers. The findings affirm the need for aggressive tobacco control in Korea in order to minimize the epidemic of smoking-caused disease.
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Cancer Causes Control · Feb 2004
Serum levels of sex hormones and breast cancer risk in premenopausal women: a case-control study (USA).
High levels of serum estrogens and androgens have been convincingly linked with an increased risk of breast cancer among postmenopausal women. By contrast, the role of blood levels of these hormones in the etiology of premenopausal breast cancer is not well understood. In a case-control study, we sought to examine associations between levels of serum estradiol, sex-hormone binding globulin (SHBG), dehydroepiandrosterone (DHEA), testosterone, androstenedione and progesterone and risk of premenopausal breast cancer. ⋯ For luteal progesterone, the RR for the highest versus lowest tertile was 0.55 (0.2-1.4). In summary, we did not find a convincing association between serum SHBG, estradiol, testosterone or androstenedione and premenopausal breast cancer risk. Observed differences between cases and controls subjects in serum levels of DHEA and luteal phase progesterone should be investigated further in large prospective studies.
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Cancer Causes Control · Dec 2003
Palliative home care reduces time spent in hospital wards: a population-based study in the Tuscany Region, Italy.
To estimate the reduction of time spent in hospital obtained through palliative home care. ⋯ Palliative home care was effective in reducing time spent in hospital during the last 3 months of life.