Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Graph theory analysis of brain connectivity data is a promising tool for studying the function of the healthy and diseased brain. The consistency of resting-state functional MRI (rsfMRI) connectivity measures across multiple scanner types is an important factor in designing multi-institutional research studies and has important implications for the potential use of this technique in a heterogeneous clinical setting. We sought to quantitatively study the interscanner variability of rsfMRI graph theory metrics obtained from healthy volunteers scanned on three different scanner platforms. ⋯ There was high consistency of graph theory metrics of rsfMRI connectivity networks among healthy volunteers scanned on three different generation 3T MRI scanners.
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Mechanical thrombectomy has been shown to be effective for acute stroke treatment, but lesions of cerebral vessels can develop thereafter. Such lesions of recanalized vessels and altered cerebral hemodynamics after mechanical thrombectomy are poorly investigated. In particular for neurosonography, data are sparse. We aimed to describe hemodynamic changes and incidence of de-novo stenosis after mechanical thrombectomy with neurosonography. ⋯ Sonographic incidence of de-novo stenosis following mechanical thrombectomy seems to be low, in line with prior angiographic studies. However, as measured by neurosonography, cerebral hemodynamic in the recanalized vessel is dynamic after thrombectomy. This result is of interest for further prospective analysis.
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There is a lack of consensus in the literature as to which body habitus parameter most influences nerve cross-sectional area (CSA). This study was specifically designed to determine if height or weight is more influential. ⋯ Weight was found to be the body habitus parameter that most influences nerve CSA. This will inform clinicians when using nerve imaging to evaluate participants at either extreme of weight.
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Assessment of the effects of microgravity on astronauts' brains using microstructural measures by utilizing quantitative MRI, before and after spaceflight would help understand the structural changes. ⋯ Gray and white matter alterations are detected by quantitative MRI before and after space flight. Our findings may be used to understand the neuroanatomical mechanisms of possible brain dysfunction or neuroplasticity in microgravity condition in the future studies.
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While AD can be definitively confirmed by postmortem histopathologic examination, in vivo imaging may improve the clinician's ability to identify AD at the earliest stage. The aim of the study was to test the performance of amyloid PET using new processing imaging algorithm for more precise diagnosis of AD. ⋯ Amyloid PET using SPM-normalized SUVR analysis showed high predictive power for the differential diagnosis of AD.