Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Medial lemniscus T2 hyperintensity (MLH) has been recently demonstrated as potential imaging marker for small vessel disease (SVD). Our purpose in this study is to improve accuracy of regions of interest (ROI) analysis for this imaging finding. ⋯ MLH seen on high threshold ROI analysis is a reliable radiologic marker in predicting SVD. ROI analysis of MLH should be performed by an experienced neuroradiologist.
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Clinical Trial
Arterial spin labeling identifies tissue salvage and good clinical recovery after acute ischemic stroke.
Arterial spin labeling (ASL) is a relatively new MR perfusion technique that requires validation. ⋯ Hyperperfusion of the initially ischemic area identified on ASL at 24 hours poststroke identifies patients with better tissue and clinical outcomes.
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Case Reports
Cerebral embolus following chiropractic manipulation in a patient with a calcified carotid artery.
Dissection of the cervicocranial vessels is the principal cause of ischemic brain injury following cervical spinal manipulation. Cervical spinal manipulation leading to cerebral embolus in the absence of dissection is not described in the literature. Current case documents cerebral embolism originating from extensively calcified internal carotid artery immediately following cervical spinal manipulation in the absence of dissection. ⋯ Calcified carotid artery may be at risk for embolization following cervical spinal manipulation. Our recommendation is that, patients with extensively calcified carotid arteries should refrain from aggressive neck maneuvers and cervical spine manipulation therapy to avoid liberation of cerebral embolus.
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Retraction Of Publication
Retraction. Neuroimaging in metabolic disorders of children.
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Comparative Study
Hippocampal magnetization transfer ratio at 3T: validation of automated postprocessing and comparison of quantification metrics.
To investigate the reliability of a novel magnetization transfer ratio (MTR) postprocessing technique for the hippocampus using histogram analysis, and compare results to more established volumetric measurements. This study is conducted in healthy volunteers as a precursor to future applications regarding progressive neurologic diseases, such as Alzheimer's disease. ⋯ Excellent scan-rescan reproducibility (ICC > .9, COV < 10%) was observed for specific MTR histogram metrics and the mean MTR approach. These results are comparable to the volumetric approach. Future studies can examine the possibility that MTR changes precede morphological changes as this study suggests that both MTR and volumetric measurements of the hippocampus can be used as reliable imaging tools.