Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
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Randomized Controlled Trial Multicenter Study
Analgesic control and functional outcome after knee arthroscopy: results of a randomized double-blinded trial comparing a hyaluronic acid supplement with bupivacaine.
Hyaluronic acid (HA) is a naturally occurring substance within normal synovial joints. Although its efficacy in treating osteoarthritis has been evaluated, it has not been established whether it is of benefit after routine arthroscopic procedures. We hypothesized that immediate supplementation with HA after completion of arthroscopy would result in improved short-term analgesic and functional outcomes after knee arthroscopy. ⋯ Routine use of HA at the time of knee arthroscopy cannot be recommended.
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Multicenter Study
Equestrian injuries caused by horse kicks: first results of a prospective multicenter study.
To analyze horse-related accidents caused by hoof kicks. ⋯ Hoof kick injuries account for a significant proportion of equine injuries and occur when riders are dismounted, most frequently when grooming without wearing protective equipment. Head and facial injuries occur most frequently and suggest that mandatory helmet and facial grill use should be considered during all horse-related activities.
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Multicenter Study
Apolipoprotein E genotype and concussion in college athletes.
To evaluate the association between apolipoprotein E (APOE) polymorphisms (E2, C/T Arg158Cys; E4, T/C Cys112Arg; and promoter, g-219t) and the history of concussion in college athletes. We hypothesized that carrying 1 or more APOE rare (or minor) allele assessed in this study would be associated with having a history of 1 or more concussions. ⋯ Carriers of all 3 APOE rare (or minor) alleles assessed in this study were nearly 10 times more likely to report a previous concussion and may be at a greater risk of concussion versus noncarriers. Promoter minor allele carriers were 8.4 times more likely to report multiple concussions and may be at a greater risk of multiple concussions versus noncarriers. Research involving larger samples of individuals with multiple concussions and carriers of multiple APOE rare alleles is warranted.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial.
To assess the efficacy and safety of celecoxib and naproxen in the treatment of acute ankle sprain. ⋯ Celecoxib is as effective as naproxen in treating acute first-degree or second-degree ankle sprains but causes significantly less dyspepsia.