Journal of magnetic resonance imaging : JMRI
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To describe what, if any, specific long T(2)-related abnormalities occur in the white matter of subjects with either phenylketonuria (PKU) or multiple sclerosis (MS). ⋯ This study supports the usefulness of increasing the data acquisition window of the multiecho T(2) relaxation sequence to better characterize the T(2) decay from pathological brain.
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J Magn Reson Imaging · Oct 2007
Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair.
To characterize the range of biventricular size and function evaluated by steady-state free precession (SSFP) cine magnetic resonance (MR) in a large cohort of patients with repaired tetralogy of Fallot (TOF), and to compare these measurements in those with a right ventricular outflow tract (RVOT) patch vs. a right ventricle-to-pulmonary artery (RV-PA) conduit. ⋯ This study provides the range and distribution of biventricular size and function, and PR measured by MRI in a large contemporary cohort of patients with repaired TOF, and demonstrates important variations in RV mechanics between patients repaired with a RVOT patch and those with an RV-PA conduit.
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J Magn Reson Imaging · Oct 2007
Whole-body diffusion-weighted imaging: technical improvement and preliminary results.
To optimize the free-breathing whole-body diffusion-weighted imaging (WB-DWI) protocol by using the short TI inversion-recovery diffusion-weighted echo-planar imaging (STIR-DWEPI) sequence and the built-in body coil. Additionally, to evaluate the feasibility of tumor screening using high-resolution three-dimensional (3D) maximum intensity projection (MIP) images. ⋯ Stable and high-resolution WB-DWI is feasible using the technical improvements described in this study. WB-DWI might have important clinical value for the detection of primary and metastatic malignancies within the whole body. The potential for diagnosis and therapeutic assessment of tumors should be further assessed in a larger patient cohort.
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J Magn Reson Imaging · Oct 2007
Multiecho reconstruction for simultaneous water-fat decomposition and T2* estimation.
To describe and demonstrate the feasibility of a novel multiecho reconstruction technique that achieves simultaneous water-fat decomposition and T2* estimation. The method removes interference of water-fat separation with iron-induced T2* effects and therefore has potential for the simultaneous characterization of hepatic steatosis (fatty infiltration) and iron overload. ⋯ The T2*-IDEAL technique has potential applications in imaging of diffuse liver disease for evaluation of both hepatic steatosis and iron overload in a single breath-hold.
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J Magn Reson Imaging · Oct 2007
Interleaved water and fat imaging and applications to lipid quantitation using the gradient reversal technique.
To implement and evaluate the gradient reversal-based chemical shift imaging technique to obtain qualitative and quantitative spatially-registered fat and water images with high imaging efficiency at very high field. ⋯ The proposed MRI technique permits interleaved water and fat imaging, with which spectrally well-separated water and fat images at the identical slice locations could be obtained in a single acquisition without increasing scan time. The technique could be used for in vivo quantitative mapping of lipid content and applied to investigations using small animal experiment models.