Journal of magnetic resonance imaging : JMRI
-
J Magn Reson Imaging · Oct 2007
Gadobenate dimeglumine-enhanced MR angiography: Diagnostic performance of four doses for detection and grading of carotid, renal, and aorto-iliac stenoses compared to digital subtraction angiography.
To determine the diagnostic performance of contrast-enhanced MR angiography (CE-MRA) with four doses of gadobenate dimeglumine for detection of significant steno-occlusive disease of the carotid, renal, and pelvic vasculature. ⋯ Significantly better diagnostic performance on CE-MRA of the renal, pelvic, and carotid arteries is achieved with a gadobenate dimeglumine dose of 0.1 mmol/kg bodyweight.
-
The principles of contrast mechanisms and fast pulse sequences underlying neurological and neuroradiological application of MRI are introduced in this part of a two-part review. In particular, the relaxation time constants T(1), T(2), and T(2) (*) are introduced, along with pulse sequences harnessing their contrast, spin-echo, fast spin echo (FSE), inversion recovery (IR), gradient recalled echo (GRE), and echo planar imaging (EPI). The use of gadolinium (Gd)-based contrast is discussed in both T(1)- and T(2) (*)-weighted sequences. ⋯ T(2) (*) sensitivity is discussed as both a source of artifact as well as a contrast mechanism (perfusion imaging with contrast agents, susceptibility weighted imaging [SWI], and blood oxygenation level dependent [BOLD] imaging). Finally, the contrast mechanism of diffusion is introduced, as well as the concept of anisotropy. From these principles, the other part of this two-part review draws upon the pulse sequences and contrast mechanisms to design disease and indication-specific protocols for state-of-the-art clinical use.
-
J Magn Reson Imaging · Oct 2007
Comparative StudySTIR turbo SE MR imaging vs. coregistered FDG-PET/CT: quantitative and qualitative assessment of N-stage in non-small-cell lung cancer patients.
To conduct a prospective comparison of the accuracy of short inversion time (TI) inversion-recovery (STIR) turbo spin-echo (SE) imaging and coregistered 2-[fluorine-18] fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET) with computed tomography (CT) (coregistered FDG-PET/CT) to assess the N-stage in non-small-cell lung cancer (NSCLC) patients. ⋯ STIR turbo SE imaging is at least as valid as coregistered FDG-PET/CT for quantitative and qualitative assessment of the N-stage for NSCLC patients.
-
J Magn Reson Imaging · Oct 2007
Three-dimensional delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) for in vivo evaluation of reparative cartilage after matrix-associated autologous chondrocyte transplantation at 3.0T: Preliminary results.
To use a 3D gradient-echo (GRE) sequence with two flip angles for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) to evaluate relative glycosaminoglycan content of repair tissue after matrix-associated autologous chondrocyte transplantation (MACT). ⋯ The 3D dual flip angle dGEMRIC technique optimized for cartilage imaging is comparable to standard T1 IR technique for T1 mapping. Furthermore, the preliminary in vivo study demonstrates the feasibility of the technique in the evaluation of MACT patients.
-
J Magn Reson Imaging · Oct 2007
Absolute quantification of cerebral blood flow in normal volunteers: correlation between Xe-133 SPECT and dynamic susceptibility contrast MRI.
To compare absolute cerebral blood flow (CBF) estimates obtained by dynamic susceptibility contrast MRI (DSC-MRI) and Xe-133 SPECT. ⋯ A reasonable positive linear correlation between MRI-based and SPECT-based CBF estimates was observed after AIF time-integral correction. The use of DSC-MRI typically results in overestimated absolute perfusion estimates and the present study indicates that this trend is further enhanced by the use of high magnetic field strength (3T).