Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Feb 2009
Relative apparent diffusion coefficient: determination of reference site and validation of benefit for detecting metastatic lymph nodes in uterine cervical cancer.
To determine the reference site for relative apparent diffusion coefficient (rADC) and to evaluate the benefit of rADC for detecting metastatic lymph nodes in uterine cervical cancer. ⋯ The renal cortex is an appropriate reference site for rADC and rADC may improve the accuracy for diagnosing metastatic lymph nodes in uterine cervical cancer.
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J Magn Reson Imaging · Feb 2009
Comparative StudyAdded value of breathhold diffusion-weighted MRI in detection of small hepatocellular carcinoma lesions compared with dynamic contrast-enhanced MRI alone using receiver operating characteristic curve analysis.
To evaluate the added value of single-breathhold diffusion-weighted MRI (DWI) in detection of small hepatocellular carcinoma (HCC) lesions (< or =2 cm) in patients with chronic liver disease, by comparing the detection sensitivity of combined DWI/conventional dynamic contrast-enhanced (DCE)-MRI to that of conventional DCE-MRI alone. ⋯ Combined use of breathhold DWI with conventional DCE-MRI helped to provide higher sensitivities than conventional DCE-MRI alone in the detection of small HCC lesions in patients with chronic liver disease.
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J Magn Reson Imaging · Feb 2009
Evaluation of measurement uncertainties in human diffusion tensor imaging (DTI)-derived parameters and optimization of clinical DTI protocols with a wild bootstrap analysis.
To quantify measurement uncertainties of fractional anisotropy, mean diffusivity, and principal eigenvector orientations in human diffusion tensor imaging (DTI) data acquired with common clinical protocols using a wild bootstrap analysis, and to establish optimal scan protocols for clinical DTI acquisitions. ⋯ Our results demonstrate that within a clinically feasible DTI scan time of about 10 minutes, a protocol with number of diffusion gradient directions close to 30 provides nearly optimal measurement results when combined with a ratio of the total number of DW images over non-DW images equal to six. Wild bootstrap can serve as a useful tool to quantify the measurement uncertainty from human DTI data.
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J Magn Reson Imaging · Feb 2009
Prediction of locally recurrent prostate cancer after radiation therapy: incremental value of 3T diffusion-weighted MRI.
To prospectively evaluate the incremental value of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) maps in addition to T2-weighted imaging (T2WI) for predicting locally recurrent prostate cancer in patients with biochemical failure after radiation therapy. ⋯ For predicting locally recurrent prostate cancer after radiation therapy, the use of combined T2WI and DWI showed a better diagnostic performance compared to T2WI.
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J Magn Reson Imaging · Feb 2009
Comparative StudyImproved fat suppression using multipeak reconstruction for IDEAL chemical shift fat-water separation: application with fast spin echo imaging.
To evaluate and quantify improvements in the quality of fat suppression for fast spin-echo imaging of the knee using multipeak fat spectral modeling and IDEAL fat-water separation. ⋯ Multipeak IDEAL fat-water separation provides improved fat suppression for T(1)-weighted and T(2)-weighted fast spin-echo imaging of the knee when compared to single-peak IDEAL and two widely used frequency-selected fat-saturation methods.