Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Nov 2013
Cerebral blood flow quantification in swine using pseudo-continuous arterial spin labeling.
To develop quantitative cerebral blood flow (CBF) imaging using pseudo-continuous arterial spin labeling (PCASL) in swine, accounting for their cerebrovascular anatomy and physiology. ⋯ This study demonstrates the feasibility of PCASL for CBF quantification in swine. Quantification of CBF using PCASL in swine can be further developed as an accessible and cost-effective model of human cerebral perfusion for investigating injuries that affect blood flow.
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J Magn Reson Imaging · Nov 2013
Volumetric late gadolinium-enhanced myocardial imaging with retrospective inversion time selection.
To develop and validate a novel free-breathing 3D radial late gadolinium-enhanced magnetic resonance imaging technique (3D LGE-MRI) with isotropic resolution and retrospective inversion time (TI) selection for myocardial viability imaging. ⋯ The 3D LGE-MRI technique demonstrated in this study is a promising alternative for the assessment of myocardial viability in patients who have difficulty sustaining breath-holds for the clinical standard 2D LGE-MRI.
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J Magn Reson Imaging · Nov 2013
ReviewDisclosing incidental findings in brain research: the rights of minors in decision-making.
MRI is used routinely in research with children to generate new knowledge about brain development. The detection of unexpected brain abnormalities (incidental findings; IFs) in these studies presents unique challenges. While key issues surrounding incidence and significance, duty of care, and burden of disclosure have been addressed substantially for adults, less empirical data and normative analyses exist for minors who participate in minimal risk research. ⋯ However, we found little discussion about the involvement of minors in decisions about disclosure of IFs in the brain, especially for IFs of low clinical significance. In response, we propose a framework for managing IFs that integrates practical considerations with explicit appreciation of rights along the continuum of maturity. This capacity-adjusted framework emphasizes the importance of involving competent minors and respecting their right to make decisions about disclosure.
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J Magn Reson Imaging · Nov 2013
Comparative StudyEffects of the use of multiple scanners and of scanner upgrade in longitudinal voxel-based morphometry studies.
To evaluate the effects of inter-scanner variability (bias) and of scanner upgrade on longitudinal changes in regional gray matter volume. ⋯ The results of our study indicate that, even with scanners of the exact same model, the use of different scanners at different time points significantly influences longitudinal morphometric results, and that scanner upgrade has effects comparable to those of using different scanners at different time points.
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J Magn Reson Imaging · Nov 2013
Comparative StudyClinical application of controlled aliasing in parallel imaging results in a higher acceleration (CAIPIRINHA)-volumetric interpolated breathhold (VIBE) sequence for gadoxetic acid-enhanced liver MR imaging.
To determine whether a controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) technique can improve the image quality of three-dimensional (3D), T1-weighted gradient echo (T1w-GRE) imaging compared with the use of a standard, parallel acquisition technique (PAT). ⋯ The CAIPIRINHA-VIBE was able to provide a higher spatial resolution, T1-weighted imaging with better image quality compared with a standard VIBE.