Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · May 2008
Comparative StudySingle-breathhold four-dimensional assessment of left ventricular volumes and function using k-t BLAST after application of extracellular contrast agent at 3 Tesla.
To prospectively determine the feasibility and accuracy of a four-dimensional (4D) k-space over time broad-use linear acquisition speed-up technique (k-t BLAST) for the evaluation of left ventricular (LV) volumes in comparison to standard multiple-breathhold cine imaging, using a 3.0 Tesla (3T) MR system. ⋯ The use of the single-breathhold 4D k-t BLAST technique for the assessment of LV volume is feasible and accurate in 3T MRI.
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J Magn Reson Imaging · May 2008
Diffusion-weighted magnetic resonance imaging allows monitoring of anticancer treatment effects in patients with soft-tissue sarcomas.
To determine if diffusion-weighted imaging (DWI) can be used as a surrogate marker of tumor response to anticancer therapy in patients with soft-tissue sarcomas. ⋯ DWI can be used as a supplement to morphologic imaging for the evaluation of tumor response to anticancer therapy in patients with soft-tissue sarcomas. As cellular changes are expected to precede morphologic changes in treated tumors, DWI performed at an early stage of fractionated therapy may provide unique prognostic information of its effectiveness.
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J Magn Reson Imaging · May 2008
Gadolinium-enhanced echo-planar T2-weighted MRI of tumors in the extracranial head and neck: feasibility study and preliminary results using a distributed-parameter tracer kinetic analysis.
To examine the feasibility of first-pass dynamic contrast-enhanced (DCE) T2-weighted MRI of tumors in the extracranial head and neck by applying a distributed-parameter (DP) tracer kinetic model to quantify the perfusion parameters. ⋯ EPI-T2-weighted DCE-MR in head and neck tumors as well as quantification of the perfusion values using DP model physiologic imaging was feasible and the promising initial results have encourages further validation studies in the future.
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J Magn Reson Imaging · May 2008
MR-guided core biopsy with MR fluoroscopy using a short, wide-bore 1.5-Tesla scanner: feasibility and initial results.
To evaluate MR fluoroscopy in a short, wide-bore 1.5T MRI suitable for near real-time biopsy guidance. ⋯ Findings of this study demonstrate that MR fluoroscopy for biopsy guidance in a short, wide-bore 1.5T scanner is feasible. This scanner combines the patient access advantages of an open-bore system with the superior image quality and speed of a high-field scanner. In our series, the HASTE sequence was best suited for MR-guidance of biopsies.
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J Magn Reson Imaging · Apr 2008
Two-dimensional 1H MR spectroscopy of the brain in human immunodeficiency virus (HIV)-infected children.
To measure cerebral metabolites in brains of human immunodeficiency virus (HIV)-infected patients using two-dimensional (2D) proton ((1)H) magnetic resonance spectroscopy (MRS), which enables more sensitive detection of metabolites at lower concentrations and delineation of the components of the different choline (Ch) groups in the frequency domain when compared to one dimensional (1D) (1)H-MRS. ⋯ We have demonstrated for the first time the feasibility of 2D-MRS in HIV-infected children and adolescents to assess cerebral metabolites and found elevated mI and elevated GABA, in the left frontal brain of clinically stable HIV-infected patients. A larger study population is needed to confirm these pilot GABA findings.