Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Anasthesiol Intensivmed Notfallmed Schmerzther · May 2014
Review[Drug interactions in intensive care medicine].
Drug-drug interactions are a common problem in elderly multi-morbid patients receiving polypharmacy. A high quantity of prescribed drugs is associated with an increase in the risk of adverse effects and drug-drug interactions. More and more medical and pharmaceutical stakeholders are involved in the drug therapy of critically ill patients. ⋯ Pharmacokinetic drug interactions concern the influence of the cytochrome P450 enzymes and transport proteins in the body. Pharmacodynamic interactions can be found, for example, as an additive effect of drugs which are combined. The relevance of both aspects must accordingly be considered and negative impact should be avoided.
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Anasthesiol Intensivmed Notfallmed Schmerzther · May 2014
Review[Invasive emergency techniques - decompression of the pleura].
On-scene invasive emergency procedures, such as cricothyroidotomy, chest drain, intraosseous puncture or even on-field-amputation, are often unavoidable, when indicated, and present a major challenge for the emergency physician. Personal, temporal or local conditions are often unsuitable. ⋯ This article presents the use of decompression of the pleura on adults and children, with reference to indication, implementation, problems and risks. It is the second part of a series of four articles on the subject of invasive emergency techniques.