Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 1997
Randomized Controlled Trial Comparative Study Clinical TrialEffects of desflurane and isoflurane on systemic vascular resistance during hypothermic cardiopulmonary bypass.
The objective of this study was to examine the dose-related effects of desflurane and isoflurane on systemic vascular resistance during hypothermic cardiopulmonary bypass. ⋯ Equi-MAC concentrations of desflurane and isoflurane had similar effects on systemic vascular resistance; 0.5 MAC maintained systemic vascular resistance; 1.0 MAC decreased systemic vascular resistance during hypothermic cardiopulmonary bypass.
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J. Cardiothorac. Vasc. Anesth. · Feb 1997
Randomized Controlled Trial Clinical TrialMethylprednisolone and full-dose aprotinin reduce reperfusion injury after cardiopulmonary bypass.
To compare the effects of low- and full-dose aprotinin to methylprednisolone (MPS) in reducing cardiopulmonary bypass (CPB)-induced interleukin-6 (IL-6) release. ⋯ These results demonstrate that MPS, 1 g before CPB, and full-dose aprotinin, but not half-dose aprotinin, achieve significant reduction in IL-6 release after CPB. These results further suggest that MPS and full-dose aprotinin may reduce reperfusion injury after CPB.
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J. Cardiothorac. Vasc. Anesth. · Feb 1997
Randomized Controlled Trial Clinical TrialIntraoperative plasmapheresis in cardiac surgery.
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J. Cardiothorac. Vasc. Anesth. · Feb 1997
Randomized Controlled Trial Clinical Trial Controlled Clinical TrialA placebo-controlled trial verifying the efficacy of milrinone in weaning high-risk patients from cardiopulmonary bypass.
To establish the efficacy of the phosphodiesterase inhibitor milrinone in facilitating weaning from cardiopulmonary bypass of high-risk patients with left ventricular dysfunction and/or pulmonary hypertension. ⋯ This placebo-controlled, double-blind study has conclusively demonstrated the benefits of milrinone in facilitating weaning of high-risk patients from cardiopulmonary bypass.
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J. Cardiothorac. Vasc. Anesth. · Feb 1997
Randomized Controlled Trial Clinical TrialModel-driven closed-loop feedback infusion of atracurium and vecuronium during hypothermic cardiopulmonary bypass.
This study was designed to investigate the performance of a computer-controlled infusion of atracurium and vecuronium during cardiac surgery requiring hypothermic cardiopulmonary bypass. ⋯ The computer-controlled infusion can be used for the administration of atracurium and vecuronium during CPB.