Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEfficacy and safety of remifentanil in coronary artery bypass graft surgery: a randomized, double-blind dose comparison study.
To compare the efficacy and safety of 3 doses of remifentanil as part of a total intravenous anesthesia technique with low-dose propofol in patients undergoing coronary artery bypass graft (CABG) surgery. ⋯ All 3 remifentanil dose regimens provided profound suppression of responses to surgical stimuli in the majority of patients. There was no apparent advantage in starting the remifentanil infusion rate above 1.0 microg/kg/min. Remifentanil is not suitable for use as a sole induction agent.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Randomized Controlled Trial Comparative Study Clinical TrialThe effect of high-frequency ventilation of the lungs on postbypass oxygenation: A comparison with other ventilation methods applied during cardiopulmonary bypass.
To compare the effect of high-frequency ventilation versus other ventilation methods applied during cardiopulmonary bypass on postbypass oxygenation. ⋯ The alveolar-arterial oxygen gradient was lower, and the PaO(2) was higher 5 minutes after bypass in patients receiving CPAP (100% O(2)) as compared with those ventilated with high-frequency ventilation.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Ventilator-associated pneumonia: Incidence, risk factors, outcome, and microbiology.
To determine the incidence, risk factors, outcome, and pathogens of ventilator-associated pneumonia (VAP) in a cardiac surgical intensive care unit (ICU). ⋯ These data suggest that by univariate analysis the risk factors for VAP were emergency surgery, COPD, reintubation, coma, steroid treatment, IABC, enteral feedings, tracheostomy, APACHE II score, prior antibiotics, and IPPV hours. On multivariate analysis, only IPPV hours and steroids were independent predictors of VAP. Pseudomonas aeruginosa is the most common pathogen associated with VAP, and the mortality is increased with VAP.
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J. Cardiothorac. Vasc. Anesth. · Feb 2003
Comparative Study Clinical TrialThe effects of remifentanil and thoracic epidural on oxygenation and pulmonary shunt fraction during one-lung ventilation.
To compare the effects of remifentanil and thoracic epidural analgesia on the hemodynamic changes and pulmonary shunt fraction during one-lung ventilation (OLV) for thoracotomy. ⋯ Both remifentanil infusion and TEA are suitable for analgesia during thoracic surgery when OLV is used. There was no significant difference in PaO(2) and Qs/Qt during each administration.