European radiology
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Review Meta Analysis
Complications following ultrasound-guided core needle biopsy of thyroid nodules: a systematic review and meta-analysis.
To identify the complication rate associated with US-guided core needle biopsy (CNB) of thyroid lesions using a systematic review and meta-analysis. ⋯ • Various complications occurred after CNB of thyroid lesions, but the pooled complication rate was low (1.11%, I 2 = 87.2%). • The pooled proportion of major complications (0.06%) was much lower than that of minor complications (1.08%). • There was no significant differences between studies on Asian vs. non-Asian groups, radiologist vs. non-radiologist groups, nodule size <20 mm vs. nodule size ≥20 mm groups, CNB vs. CNB-plus-FNA groups, or studies performed before 2012 vs. after 2012.