International journal of obstetric anesthesia
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Int J Obstet Anesth · Jan 2011
Randomized Controlled Trial Comparative StudyLow-dose ketamine with multimodal postcesarean delivery analgesia: a randomized controlled trial.
Ketamine at subanesthetic doses has analgesic properties that have been shown to reduce postoperative pain and morphine consumption. We hypothesized that intravenous ketamine 10mg administered during spinal anesthesia for cesarean delivery, in addition to intrathecal morphine and intravenous ketorolac, would decrease the incidence of breakthrough pain and need for supplemental postoperative analgesia. ⋯ We found no additional postoperative analgesic benefit of low-dose ketamine during cesarean delivery in patients who received intrathecal morphine and intravenous ketorolac. Subjects who received ketamine reported lower pain scores 2weeks postpartum.