International journal of obstetric anesthesia
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Int J Obstet Anesth · May 2016
Randomized Controlled TrialEffect of preoperative pregabalin on post-caesarean delivery analgesia: a dose-response study.
We hypothesised that preoperative administration of a single-dose of pregabalin would be associated with lower morphine consumption after uncomplicated caesarean delivery. ⋯ In our study, preoperative administration of pregabalin 300mg reduced postoperative morphine consumption and early postoperative pain in parturients undergoing elective caesarean delivery, although maternal side effects were more common.