American heart journal
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American heart journal · Mar 2003
Randomized Controlled Trial Multicenter Study Clinical TrialSustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: results from the GUSTO-III trial.
In many patients, ventricular arrhythmias will develop early after acute myocardial infarction. We studied the incidence, timing, and outcomes of such arrhythmias in the international Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries (GUSTO)-III trial. ⋯ Despite thrombolysis, inhospital ventricular arrhythmias are associated with higher 30-day and 1-year mortality rates after acute myocardial infarction, particularly when occurring later during the initial hospitalization. Better therapies are needed to improve outcomes of these arrhythmias.