The Annals of pharmacotherapy
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Randomized Controlled Trial
Subcutaneous tramadol infiltration at the wound site versus intravenous administration after pyelolithotomy.
Recently, the peripheral anesthetic effect of tramadol has been the theme of many studies. The postoperative analgesic effects of subcutaneous wound infiltration with tramadol have not been extensively studied and compared with those of intravenous administration. ⋯ Subcutaneous wound infiltration with tramadol reduces postoperative opioid consumption and produces less nausea and vomiting than does intravenous administration.