The Annals of pharmacotherapy
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Meta Analysis Comparative Study
A Comparison of the Efficacy and Tolerability of the Treatments for Sciatica: A Network Meta-Analysis.
There remains a lack of a systematic summary of the efficacy and safety of various medicines for sciatica, and discrepancies among these exist. ⋯ Intravenous and subcutaneous anti-TNF-α were identified as the optimal treatments for both acute + chronic sciatica patients and acute sciatica patients. In addition, the epidural steroid was also recommended as a good intervention due to its superiority in reducing ODI.