The Annals of pharmacotherapy
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Multicenter Study
Comparison of 3 Different Prothrombin Complex Concentrate Regimens for Emergent Warfarin Reversal: PCCWaR Study.
The ideal dose and specific prothrombin complex concentrate (PCC) for warfarin reversal is unknown. ⋯ There was no difference in the ability to achieve a post-PCC INR of ≤1.4 between 3 different PCC regimens for warfarin reversal. Additional research is warranted to determine the ideal dose and PCC agent for warfarin reversal.