Dermatology : international journal for clinical and investigative dermatology
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Dermatology (Basel) · Jan 2008
Randomized Controlled TrialRelationship between clinical response to therapy and health-related quality of life outcomes in patients with moderate to severe plaque psoriasis.
Health-related quality of life (HRQOL) outcomes are associated with clinical response to treatment in psoriasis. However, the association between HRQOL outcomes and more substantial degrees of Psoriasis Area and Severity Index (PASI) response and physician and patient global ratings remains ill defined. ⋯ Improvement in PASI response of >75% corresponded to improvements in HRQOL outcome measures for patients with moderate to severe psoriasis. PASI 90 or 100 responders had greater improvements in DLQI total score than PASI 75 responders.