Journal of vascular and interventional radiology : JVIR
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J Vasc Interv Radiol · Dec 2010
Randomized Controlled Trial Multicenter StudyTROPICS 1: a phase III, randomized, double-blind, placebo-controlled study of tenecteplase for restoration of function in dysfunctional central venous catheters.
To evaluate the efficacy and safety of the thrombolytic tenecteplase, a fibrin-specific recombinant tissue plasminogen activator, for restoring function to dysfunctional central venous catheters (CVCs). ⋯ Tenecteplase was efficacious for restoration of catheter function in these study patients with dysfunctional CVCs.