Journal of diabetes and its complications
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J. Diabetes Complicat. · Jul 2014
Randomized Controlled Trial Multicenter StudyCost implications of the use of basal insulin glargine in people with early dysglycemia: the ORIGIN trial.
The cost implications of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial were evaluated using a prespecified analysis plan. ⋯ From a global perspective basal insulin glargine use in ORIGIN incurred greater costs than standard care using older generic drugs. Nevertheless, the cost difference fell with time such that the intervention was cost-neutral by the last year.