American journal of clinical pathology
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Am. J. Clin. Pathol. · Jun 2014
Reducing blood utilization by implementation of a type-and-screen transfusion policy a single-institution experience.
The Blood Utilization Committee implemented a standardized protocol for the preoperative blood order for cardiac patients. The aim of our study was to assess the improvement in blood utilization using the crossmatch to transfusion ratio (C:T). ⋯ Implementing exact guidelines, with the introduction of a type-and-screen concept, allowed more efficient blood usage.
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Meningiomas are slow-growing intracranial/intraspinal tumors, with a wide range of histopathologic variants. The more aggressive atypical and malignant types can disseminate via the venous system, lymphatic, system, or cerebrospinal fluid, with the lung and pleura being the most common sites of extracranial metastases. A case of metastatic meningioma with high expression of CD90 was spotted during a review of flow cytometry data for lung malignancies. Therefore, we have analyzed CD90 expression in a series of meningioma metastases with their corresponding primary tumors and in a series of 92 primary meningioma tumors. ⋯ CD90 is a biomarker overexpressed in atypical meningioma, with a potential role in metastatic switch of this tumor.