Acta paediatrica
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Randomized Controlled Trial
Effect of high-dose paracetamol on needle procedures in children with cancer--an RCT.
The aim was to investigate whether children experience less pain, fear and/or distress when they receive high-dose paracetamol compared with placebo, using a needle insertion in a subcutaneously implanted intravenous port as a model. ⋯ Paracetamol provides no additive effect in reducing pain, fear and distress when combined with topical anaesthesia in children undergoing port needle insertion.