Paediatric anaesthesia
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Paediatric anaesthesia · Nov 2003
Randomized Controlled Trial Comparative Study Clinical TrialPretreatment with intravenous ketamine reduces propofol injection pain.
Paediatric procedural sedation using propofol has been shown to be safe and effective and is widely used. Pain at the injection site is a frequent complaint and can be particularly distressing for children, especially for those undergoing repeated procedures. Ketamine has analgesic properties and can diminish the incidence of propofol infusion pain in adults. The aim of the study was to investigate whether pretreatment with ketamine would reduce infusion line pain in propofol sedation in children. ⋯ Pretreatment with ketamine (0.5 mg.kg-1) is very effective in preventing propofol infusion pain.