Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Clinical TrialIs tissue coring a real problem after caudal injection in children.
The aim of this study was to determine whether tissue coring occurs with 22-G hollow needle and 22-G caudal block needle during caudal injection in children, as well as evaluating the nature of the coring material if it did occur. ⋯ The incidence of transporting nucleated epidermal cells with no mitotic activity from stratum spinosum during puncture for caudal block is low and no differences exist between different types of needle used. However, it may also suggest that transporting nucleated cells with mitotic activity from the stratum basale may be possible during caudal puncture.
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialJet injector compared with oral midazolam for preoperative sedation in children.
This study compared onset of sedation and satisfaction with two needleless jet injectors with the oral route for the administration of midazolam. ⋯ Despite children being less satisfied with Bioject injection of midazolam, the procedure is safe, effective and provides a more rapid onset of preoperative sedation in children than either the J-Tip injection or oral route.
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialEffectiveness of morphine via thoracic epidural vs intravenous infusion on postthoracotomy pain and stress response in children.
Thoracotomy causes severe pain in the postoperative period. The aim was to evaluate effectiveness of two pain treatment methods with morphine on postthoracotomy pain and stress response. ⋯ Single dose TEP morphine offers no advantage over INF for pain treatment for thoracotomy in children and neither technique provided suppression of stress hormones in the first 24 h postoperatively.
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Clinical TrialThe effect of premedication with OTFC, with or without ondansetron, on postoperative agitation, and nausea and vomiting in pediatric ambulatory patients.
The purpose of this study was to evaluate, in the pediatric ambulatory surgical population, the efficacy of: (i) oral transmucosal fentanyl citrate (OTFC), when given preoperatively, to reduce postoperative excitement associated with sevoflurane, and (ii) intravenous ondansetron to reduce postoperative nausea and vomiting (PONV) associated with OTFC. ⋯ Even though OTFC reduced early postoperative agitation the increase in side effects, namely PONV and prolonged recovery times, limits its clinical usefulness. The study demonstrates the tradeoffs between anxiety and agitation vs vomiting, respiratory events and prolonged recovery times. Ambulatory pediatric patients undergoing procedures in which opioids would be routinely used might benefit the most from OTFC combined with ondansetron as part of the anesthetic technique.