Paediatric anaesthesia
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Paediatric anaesthesia · Feb 2005
Randomized Controlled Trial Comparative Study Clinical TrialCaudal additives for postoperative pain management in children: S(+)-ketamine and neostigmine.
The aim of the present pilot study was to compare the analgesic efficacy of S(+)-ketamine either alone or in combination with neostigmine for caudal blockade in pediatric surgery. ⋯ This pilot study demonstrates equianalgesic effects on postoperative pain relief in children with both caudal S(+)-ketamine 1 mg.kg(-1) and caudal S(+)-ketamine 0.5 mg.kg(-1) plus neostigmine 10 microg.kg(-1). Further studies are required to confirm adoption of caudal neostigmine into routine clinical practice.