Paediatric anaesthesia
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Paediatric anaesthesia · Jul 2005
Risk factors influencing inadvertent hypothermia in infants and neonates during anesthesia.
The factors affecting the thermal status in neonates and infants undergoing general anesthesia are not yet investigated in detail. We evaluated the factors leading to intraoperative hypothermia in 60 neonates and infants. ⋯ The type of surgery and the OR temperature are the main factors for decrease of the core temperature in neonates and infants. In neonates, the core temperatures are less stable, regardless of OR temperature and type of surgery. In high OR temperature, infants can stabilize their core temperature better than neonates.
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Paediatric anaesthesia · Jul 2005
Randomized Controlled Trial Clinical TrialGiving parents written information about children's anesthesia: are setting and timing important?
Research indicates that parents wish to receive more information and are anxious about anesthesia prior to their child's surgery. ⋯ Parents have unmet information needs related to children's anesthetic care. Written information may improve parent knowledge and enhance satisfaction, but the setting and timing of information delivery are also important to consider.
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Paediatric anaesthesia · Jul 2005
Clinical TrialMarked variation in oxycodone pharmacokinetics in infants.
The pharmacokinetics of oxycodone (13-hydroxy-7,8-dihydrocodeinone) has been studied in adults and in children who are older than 6 months but there is no information on the disposition of oxycodone in neonates and young infants. The aim of this study was to study the pharmacokinetics of oxycodone in infants varying in age from 0 to 6 months. ⋯ The values for Cl and t(1/2) varied greatly between the subjects. This variability was most pronounced in the two youngest groups. Routine dosing of oxycodone in young infants may be dangerous. The dose of oxycodone must be titrated individually.
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Paediatric anaesthesia · Jul 2005
Case ReportsProlonged infusion of dexmedetomidine for sedation following tracheal resection.
Dexmedetomidine is a centrally acting alpha-2 adrenergic agonist that is currently approved by the US Food and Drug Administration for short-term use (< or = 24 h) to provide sedation in adults in the ICU. This drug has been shown to be efficacious in adult medical and surgical patients in providing sedation, anxiolysis, and analgesia. ⋯ To date, there are few publications of the use of this drug in children, and prolonged infusion has not been described. We report our use of dexmedetomidine in a child during a 4-day period of mechanical ventilation following tracheal reconstruction for subglottic stenosis.