Paediatric anaesthesia
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Paediatric anaesthesia · Jul 2005
Clinical TrialMarked variation in oxycodone pharmacokinetics in infants.
The pharmacokinetics of oxycodone (13-hydroxy-7,8-dihydrocodeinone) has been studied in adults and in children who are older than 6 months but there is no information on the disposition of oxycodone in neonates and young infants. The aim of this study was to study the pharmacokinetics of oxycodone in infants varying in age from 0 to 6 months. ⋯ The values for Cl and t(1/2) varied greatly between the subjects. This variability was most pronounced in the two youngest groups. Routine dosing of oxycodone in young infants may be dangerous. The dose of oxycodone must be titrated individually.
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Paediatric anaesthesia · Jul 2005
Case ReportsUse of CobraPLA for airway management in a neonate with Desbuquois syndrome. Case report and anesthetic implications.
We present the anesthetic management of an infant with Desbuquois syndrome (a rare form of micromelic dwarfism) with a possible difficult airway. The anesthetic implications of this syndrome are presented. ⋯ It was easy to insert and provided satisfactory conditions for positive pressure ventilation. The CobraPLA provides another option for airway management.
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Paediatric anaesthesia · Jul 2005
Randomized Controlled Trial Clinical TrialClonidine administered as adjuvant for bupivacaine in ilioinguinal-iliohypogastric nerve block does not prolong postoperative analgesia.
Coadministration of clonidine with local anesthetics is associated with improvement of the quality of peripheral nerve block and significant prolongation of postoperative analgesia. Better analgesia has been reported with clonidine in ilioinguinal nerve block compared with caudal use. The object of this study was to determine whether adding of 1 microg.kg(-1) clonidine to bupivacaine 0.25% in ilioinguinal-iliohypogastric nerve block prolongs postoperative analgesia in children. ⋯ Our study failed to demonstrate any advantage in addition of 1 microg.kg(-1) clonidine to 0.25% bupivacaine for ilioinguinal-iliohypogastric nerve block compared with bupivacaine 0.25% alone.
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Paediatric anaesthesia · Jul 2005
Randomized Controlled Trial Clinical TrialGiving parents written information about children's anesthesia: are setting and timing important?
Research indicates that parents wish to receive more information and are anxious about anesthesia prior to their child's surgery. ⋯ Parents have unmet information needs related to children's anesthetic care. Written information may improve parent knowledge and enhance satisfaction, but the setting and timing of information delivery are also important to consider.