Paediatric anaesthesia
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Paediatric anaesthesia · Aug 2005
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialTolerance and analgesic efficacy of a new i.v. paracetamol solution in children after inguinal hernia repair.
A new intravenous (i.v.) formulation of paracetamol and propacetamol (prodrug of paracetamol) were compared to determine tolerance and relative analgesic efficacy during the first 6 h after inguinal hernia repair performed under general anesthesia combined with ilioinguinal block in children. ⋯ A single infusion of i.v. paracetamol 15 mg.kg(-1) produced analgesia similar to a single infusion of propacetamol 30 mg.kg(-1) following inguinal hernia repair in children. Paracetamol i.v. 15 mg.kg(-1) was better tolerated at the injection site than propacetamol.