Paediatric anaesthesia
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Paediatric anaesthesia · Jun 2006
Randomized Controlled Trial Comparative StudyTramadol vs morphine during adenotonsillectomy for obstructive sleep apnea in children.
Optimal analgesia for children undergoing adenotonsillectomy for obstructive sleep apnea (OSA) is controversial. Tramadol may represent a superior choice over morphine in this group, with a potential to cause less postoperative sedation and respiratory depression. Optimal perioperative analgesia may allow expensive and time-consuming preoperative work-up and postoperative monitoring to be rationalized. ⋯ Tramadol may be a suitable drug for children undergoing adenotonsillectomy for OSA. Further work is required to investigate this.
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Paediatric anaesthesia · Jun 2006
Randomized Controlled Trial Comparative StudyOral sedation with midazolam and diphenhydramine compared with midazolam alone in children undergoing magnetic resonance imaging.
The purpose of this study was to compare the safety and efficacy of oral midazolam and midazolam-diphenhydramine combination to sedate children undergoing magnetic resonance imaging (MRI). ⋯ Our study indicates that the combination of oral diphenhydramine with oral midazolam resulted in safe and effective sedation for children undergoing MRI. The use of this combination might be more advantageous compared with midazolam alone, resulting in less sedation failure during MRI.