Paediatric anaesthesia
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Paediatric anaesthesia · Aug 2007
Randomized Controlled TrialA ketamine-propofol admixture does not reduce the pain on injection compared with a lidocaine-propofol admixture.
Propofol injection pain is a well-known problem in pediatric anesthesia. Premixture of lidocaine with propofol although effective does not abolish injection pain in all children. Promising results have been reported with pretreatment of the vein with ketamine. The purpose of this prospective, double-blind randomized, clinical trial with active control was to evaluate the efficacy of premixing propofol with ketamine in the prevention of injection pain in children. ⋯ Injection pain was twice as common with ketamine-propofol admixture than with lidocaine-propofol admixture.