Paediatric anaesthesia
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Paediatric anaesthesia · Aug 2008
Randomized Controlled Trial Comparative StudyComparison of sevoflurane and ketamine for anesthetic induction in children with congenital heart disease.
Sevoflurane is widely used in pediatric anesthesia for induction. Ketamine has been preferred in pediatric cardiovascular anesthesia. Aim of this study was to compare the hemodynamic effects and the speed of ketamine and sevoflurane for anesthesia induction in children with congenital heart disease. ⋯ Ketamine appears a good alternative for induction in patients with congenital heart disease. It permits preservation of hemodynamic stability with minimal side effects.
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Paediatric anaesthesia · Aug 2008
Randomized Controlled TrialRemifentanil for percutaneous intravenous central catheter placement in preterm infant: a randomized controlled trial.
There is limited evidence on the analgesic efficacy of opioids during percutaneous intravenous central catheter (PICC) insertion in preterm infants. ⋯ Low-dose remifentanil has a measurable, synergic analgesic effect in combination with 12% sucrose and non-nutritive sucking, but does not make PICC easier or quicker.
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Paediatric anaesthesia · Aug 2008
Randomized Controlled TrialDexmedetomidine disposition in children: a population analysis.
There are few data describing dexmedetomidine population pharmacokinetics (PK) in children (0-15 years) despite increasing use. ⋯ Clearance in neonates is approximately one-third of that described in adults, consistent with immature elimination pathways. Maintenance dosing, which is a function of clearance, should be reduced in neonates and infants when using a target concentration approach.