Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2014
Randomized Controlled TrialPostoperative analgesia using diclofenac and acetaminophen in children.
Diclofenac dosing in children for analgesia is currently extrapolated from adult data. Oral diclofenac 1.0 mg·kg(-1) is recommended for children aged 1-12 years. Analgesic effect from combination diclofenac/acetaminophen is unknown. ⋯ Combination therapy can be used to achieve similar analgesia with lower doses of both drugs.
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Paediatric anaesthesia · Sep 2014
Randomized Controlled Trial Multicenter StudyA novel balanced isotonic sodium solution vs normal saline during major surgery in children up to 36 months: a multicenter RCT.
The use of isotonic electrolytic solutions for the intraoperative fluid management in children is largely recognized, but the exact composition still needs to be defined. ⋯ Sterofundin is safer than normal saline in protecting young children undergoing major surgery against the risk of increasing plasma chlorides and the subsequent metabolic acidosis.
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Paediatric anaesthesia · Sep 2014
Randomized Controlled TrialUltrasound-guided rectus sheath block or wound infiltration in children: a randomized blinded study of analgesia and bupivacaine absorption.
Rectus sheath block can provide analgesia following umbilical hernia repair. However, conflicting reports on its analgesic effectiveness exist. No study has investigated plasma local anesthetic concentration following ultrasound-guided rectus sheath block (USGRSB) in children. ⋯ USGRSB provides more effective analgesia than WI for umbilical hernia repair. USGRSB with 1 mg·kg(-1) 0.25% bupivacaine is associated with safe plasma bupivacaine concentration that peaks higher and later than WI. Caution against using larger volumes of higher concentration local anesthetic for USGRSB is advised.