Paediatric anaesthesia
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Paediatric anaesthesia · Feb 2020
Multicenter StudyAirway management and perioperative adverse events in children with mucopolysaccharidoses and mucolipidoses: a retrospective cohort study.
Children suffering from mucopolysaccharidoses (subtypes I, II, III, IV, VI, and VII) or mucolipidoses often require anesthesia, but are at high risk for perioperative adverse events. However, the impact of the disease subtype and the standard of care for airway management are still unclear. ⋯ The disease subtype and primary airway technique were the most important independent risk factors for perioperative adverse events. Our findings indicate that in MPS/ML children with predicted difficult airway indirect techniques should be favored for the first tracheal intubation attempt.