Paediatric anaesthesia
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Paediatric anaesthesia · Aug 2022
The Association of Severe Pain Experienced in the PICU and Post-Discharge Health-Related Quality of Life: A Retrospective Cohort Study.
Pain may be a modifiable risk factor for lower health-related quality of life after pediatric critical illness. ⋯ Children who experience severe pain in the pediatric intensive care unit have lower postdischarge health-related quality of life adjusting for baseline health-related quality of life, particularly among children who have undergone surgery. Attention to pain management may be important to improve postdischarge health-related quality of life.
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Paediatric anaesthesia · Aug 2022
Patient and Operative Factors Associated with Unanticipated Intensive Care Admission and Outcomes Following Posterior Fossa Decompressions in Children: A Retrospective Study.
Posterior fossa decompression for Chiari I Malformation is a common pediatric neurosurgical procedure. We sought to identify the impact of anesthesia-related intraoperative complications on unanticipated admission to the intensive care unit and outcomes following posterior fossa decompression. ⋯ Our study demonstrates that although anesthesia-related intraoperative complications during posterior fossa decompression are infrequent, they are associated with an increased risk of an unanticipated admission to the intensive care unit.
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Paediatric anaesthesia · Aug 2022
Observational StudyThe impact of modified fluid gelatin 4% in a balanced electrolyte solution on plasma osmolality in children - a non-interventional observational study.
Intravenous fluids for perioperative infusion therapy should be isotonic to maintain the body fluid homeostasis in children. Modified fluid gelatin 4% in a balanced electrolyte solution has a theoretical osmolarity of 284 mosmol L-1 , and a real osmolality of 264 mosmol kg H2 O-1 . Because both values are lower than those of 0.9% saline or plasma, gelatin would be expected to be hypotonic in-vitro and in-vivo. ⋯ Gelatin in a balanced electrolyte solution has isotonic characteristics in-vitro and in-vivo, despite the low theoretical osmolarity, probably caused by the (unmeasured) negative charges in the gelatin molecules contributing to the plasma osmolality. For a better evaluation of the (real) tonicity of gelatin-containing solutions, we suggest to calculate the osmolality (mosmol kg H2 O-1 ) using Zander's formula.