Paediatric anaesthesia
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Paediatr Anaesth
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Paediatric anaesthesia · Nov 2015
Changes of epidural blood flow after epidural administration of epinephrine in young rats.
For caudal epidural analgesia, the needle is inserted at a site where vessels are abundant. To avoid complications related to intravascular administration of the local anesthetic, epinephrine is usually added, but there is no evidence about the safety of epidural administration of epinephrine in pediatric patients. The objective of this study was to assess the changes in epidural blood flow after epidural injection of epinephrine in young rats. ⋯ Administration of epinephrine into the epidural space was safe in young rats. While reduction of epidural blood flow was observed, there was no spinal ischemia.