Paediatric anaesthesia
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Paediatric anaesthesia · Apr 2007
Clinical TrialChanges of bispectral index during recovery from general anesthesia with 2% propofol and remifentanil in children.
The bispectral (BIS) index is a pharmacodynamic measure of the effect of anesthesia on the central nervous system. The aim of this study was to investigate the relationship between BIS index and predicted plasma concentration of propofol delivered by target controlled infusion (TCI) during emergence in children. ⋯ In preschool children, BIS moderately correlated with the predicted plasma concentration of propofol.
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Paediatric anaesthesia · Apr 2007
Clinical TrialEarly administration of surfactant in spontaneous breathing with nCPAP: feasibility and outcome in extremely premature infants (postmenstrual age
Spontaneous breathing supported by nasal continuous positive airway pressure (nCPAP) is thought to have some advantages compared with mechanical ventilation in extremely premature infants. In addition, early or prophylactic surfactant administration has been shown to be superior to delayed use. A strategy to combine these two principles was tested in our neonatal intensive care unit (NICU). The aim of this feasibility study was to describe the procedure and compare short-term results with a historical control. ⋯ Surfactant administration during nCPAP is feasible. First results indicate that early complications are rare. This warrants a prospective randomized trial.
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Paediatric anaesthesia · Apr 2007
Case ReportsA combination of total intravenous anesthesia and thoracic epidural for thymectomy in juvenile myasthenia gravis.
Juvenile myasthenia gravis is the acquired form of the disease in children and presents with ocular signs, fatigability, weakness and bulbar problems. The majority of patients demonstrate thymic hyperplasia and have been shown to benefit from thymectomy. ⋯ Two cases of thymectomy are presented where anesthesia was provided using a combination of TIVA and thoracic epidural analgesia. Both patients tolerated the technique well and had an uncomplicated perioperative course.