Paediatric anaesthesia
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Paediatric anaesthesia · Jun 2013
Review Meta AnalysisOpioid-sparing effects of perioperative paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) in children.
Addition of paracetamol or NSAIDs significantly reduces post-operative opioid consumption in children, although not demonstrably opioid side effects.
pearl -
Paediatric anaesthesia · Jun 2013
Review Meta AnalysisOpioid-sparing effects of perioperative paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) in children.
Addition of paracetamol or NSAIDs significantly reduces post-operative opioid consumption in children, although not demonstrably opioid side effects.
pearl -
Paediatric anaesthesia · Feb 2013
Review Meta AnalysisEfficacy and safety of intraoperative dexmedetomidine for acute postoperative pain in children: a meta-analysis of randomized controlled trials.
Aim of the current meta-analysis was to assess the effects of intraoperative dexmedetomidine on postoperative pain, analgesic consumption, and adverse events in comparison with placebo or opioids in children undergoing surgery. ⋯ This meta-analysis revealed a lower risk for postoperative pain and the need for postoperative opioids following intraoperative dexmedetomidine in comparison with placebo or opioids in children undergoing surgery; however, the influence of dexmedetomidine on postoperative opioid consumption is less clear. Although there were only a limited number of adverse events, further studies focusing on procedure specific dexmedetomidine dosing and adverse events are urgently needed.
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Paediatric anaesthesia · Jan 2013
ReviewA literature review on flow-rate variability in neonatal IV therapy.
To provide an overview of factors influencing the flow rate in intravenous (IV) therapy for newborns. ⋯ Flow-rate variability in IV therapy and its clinical relevance are due to the preprogrammed flow rate, the hydrostatic pressure changes, the complete IV administration set compliance and the type of substances supplied to the patient. To improve IV therapy, the internal compliance of the complete IV administration set should be minimized and the highest possible preprogrammed flow rate should be used in combination with small syringes and low-resistance valves.
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Paediatric anaesthesia · Jan 2013
ReviewAnesthesia for surgery related to craniosynostosis: a review. Part 2.
The management of children with craniosynostosis is multidisciplinary and has evolved significantly over the past five decades. The treatment is primarily surgical. ⋯ The first part described the syndromes associated with craniosynostosis, the provision of services in the UK, surgical techniques, preoperative issues and induction and maintenance of anesthesia. This second part will explore hemorrhage control, the use of blood products, metabolic disturbance and postoperative issues.