Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialJet injector compared with oral midazolam for preoperative sedation in children.
This study compared onset of sedation and satisfaction with two needleless jet injectors with the oral route for the administration of midazolam. ⋯ Despite children being less satisfied with Bioject injection of midazolam, the procedure is safe, effective and provides a more rapid onset of preoperative sedation in children than either the J-Tip injection or oral route.
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Paediatric anaesthesia · Sep 2004
Multicenter Study Clinical TrialRopivacaine in neonates and infants: a population pharmacokinetic evaluation following single caudal block.
The aims of this study were to evaluate pharmacokinetics, efficacy and safety of ropivacaine in infants aged 0-12 months following a single caudal injection. ⋯ Following a caudal block with ropivacaine 2 mg x kg(-1) plasma concentrations of unbound ropivacaine were well below threshold levels for toxicity in adults. Apparent volume of distribution is unchanged, apparent unbound clearance increases and the terminal half-life decreases with age in 0-12-month-old neonates and infants. The postoperative pain management provided adequate analgesia and was well tolerated.
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialEffectiveness of morphine via thoracic epidural vs intravenous infusion on postthoracotomy pain and stress response in children.
Thoracotomy causes severe pain in the postoperative period. The aim was to evaluate effectiveness of two pain treatment methods with morphine on postthoracotomy pain and stress response. ⋯ Single dose TEP morphine offers no advantage over INF for pain treatment for thoracotomy in children and neither technique provided suppression of stress hormones in the first 24 h postoperatively.
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Anesthetic management of a 3-month-old boy with Beckwith-Wiedemann syndrome for bronchoscopy is reported. Management may be complicated by a difficult airway, congenital heart disease, and hypoglycemia. We did not have difficulty in airway management either with tracheal intubation or rigid bronchoscopy, but we could not extubate the baby because of tracheomalacia.