Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2004
Frequency of anesthesia-related complications in children with Down syndrome under general anesthesia for noncardiac procedures.
Craniofacial and cardiac anomalies of Down syndrome (DS; trisomy 21) would seem to place these patients at higher risk of anesthesia-related complications (ARCs), but to date no comprehensive large-scale study has quantified this risk. ⋯ Comprehensive reporting is needed to capture all significant adverse events. The incidences of bradycardia on induction, natural airway obstruction, and postintubation (or instrumentation) croup were significantly higher in the DS noncardiac group compared with the remaining population. Current anesthesia techniques and agents must be compared using quantitative QA data to ensure use of the safest options for each patient.
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Paediatric anaesthesia · Sep 2004
Case ReportsCombined general and epidural anesthesia for a child with alagille syndrome: a case report.
Alagille syndrome (syndromic paucity of interlobular bile ducts) is the most common form of familial intrahepatic cholestasis. We describe the perioperative management of a pediatric patient with Alagille syndrome undergoing ileal exclusion and the specific issues associated with epidural anesthesia with this syndrome.
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Paediatric anaesthesia · Sep 2004
Editorial CommentGetting the best from pediatric pharmacokinetic data.