American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Nov 1999
Randomized Controlled Trial Clinical TrialThe effect of magnesium sulfate on fetal heart rate parameters: A randomized, placebo-controlled trial.
We sought to determine the effect of magnesium sulfate on fetal heart rate baseline value, variability, and acceleration-deceleration pattern. ⋯ Prolonged administration of magnesium sulfate was associated with decreased fetal heart rate baseline values and variability. Given the small magnitude of these changes, the clinical significance of these findings is questionable. Magnesium sulfate inhibition of the increasing number of accelerations with gestational age needs to be considered when fetal well-being is assessed.
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Am. J. Obstet. Gynecol. · Nov 1999
Randomized Controlled Trial Comparative Study Clinical TrialA randomized comparison of oral misoprostol versus Foley catheter and oxytocin for induction of labor at term.
We sought to compare the efficacy and safety of oral misoprostol administered to patients with the efficacy and safety in a control group treated with a Foley catheter and oxytocin for induction of labor. ⋯ Oral misoprostol is as effective as oxytocin-Foley catheter for inducing labor in multiparous women. Misoprostol appears less efficacious in nulliparous patients.