American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of various routes and dosages of misoprostol for cervical ripening and the induction of labor.
The purpose of this study was to compare the efficacy of different routes of misoprostol administration for cervical ripening and the induction of labor. ⋯ At the doses studied, induction of labor with vaginally administered misoprostol is more efficacious than either oral-plus-vaginal or oral-only route of administration.
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialA randomized controlled trial comparing oxytocin administration before and after placental delivery in the prevention of postpartum hemorrhage.
To determine if the timing of the administration of prophylactic oxytocin influences the incidence of postpartum hemorrhage caused by uterine atony, retained placenta, and third-stage duration. ⋯ The administration of prophylactic oxytocin before placental delivery does not reduce the incidence of postpartum hemorrhage or third-stage duration, when compared with giving oxytocin after placental delivery. Early administration, however, does not increase the incidence of retained placenta.
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Am. J. Obstet. Gynecol. · Oct 2001
Comparative StudyThe effect of sequential use of vacuum and forceps for assisted vaginal delivery on neonatal and maternal outcomes.
To determine the risk of neonatal and maternal disease associated with the sequential use of vacuum and forceps compared with spontaneous vaginal delivery. ⋯ Sequential use of vacuum and forceps is associated with increased risk of both neonatal and maternal injury.
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Am. J. Obstet. Gynecol. · Oct 2001
Comparative StudyOutcomes of trial of labor following previous cesarean delivery among women with fetuses weighing >4000 g.
To compare outcomes at term of a trial of labor in women with previous cesarean delivery who delivered neonates weighing > 4000 g versus women with those weighing < or = 4000 g. ⋯ A trial of labor after previous cesarean delivery may be a reasonable clinical option for pregnant women with suspected birth weights of > 4000 g, given that the rate of uterine rupture associated with these weights does not appear to be substantially increased when compared to lower birth weights. However, some caution may apply when considering a trial of labor in women with infants weighing > 4250 g. In these women with infants weighing > 4000 g, the likelihood of successful vaginal delivery, although lower than for neonates weighing < or = 4000 g, is still 60%.
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Am. J. Obstet. Gynecol. · Oct 2001
Randomized Controlled Trial Comparative Study Clinical TrialRectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery.
To compare rectally administered misoprostol to intravenously administered oxytocin for the management of third-stage labor. ⋯ Rectal misoprostol (400 microg) was no more effective than intravenous oxytocin in preventing postpartum hemorrhage.